1. Post-translational modifications in collagen/Order and location of various post-translational processing of collagen 2. DNA packaging in metaphase chromosomes 3. Possible roles of modified histones 4. Major features of human mitochondrial DNA 5. Viral integration and transposons in human genome 6. Structure, function and inhibitors of DNA topoisomerases 7. DNA damage – causes, types, repair pathways and repair fedality 8. Double stranded break repair mechanisms 9. Transcription cycle 10. Transcription control regions for eukaryotic genes 11. Post-trancriptional modification of primary transcript 12. Mechanism of intron removal and alternative splicing 13. Alternative promotor utilization 14. Biogenesis and function of miRNA 15. Degeneracy of genetic code, concept and mechanism of wobbling phenomenon 16. Properties of genetic code 17. Point mutations and frame shift mutations 18. Circularization of mRNA during translation 19. Role of methyl-GTP cap and poly-A tail in translation 20. Antibiotics inhibiting protein synthesis 21. cis and trans epigenetic signals 22. Propagation of epigenetic signal after DNA replication 23. Properties of enhancers 24. DNA motifs 25. Various ways of gene regulation 26. Regulation of mRNA stability 27. Restriction - Enzymes used in recombinant DNA research 28. structure pf plasmid pBR322 and its use in recombinant DNA technology 29. genomic and cDNA library 30. DNA sequencing by Sanger's 31. Transgenic animals and knockout animals 32. Hypoxia induced molecular events leading to altered gene expression